Scientists at Oxford University have discovered a gene that can double the risk of respiratory failure that leads to the death of corona patients, according to what was published by Nature Genetics.
The researchers noted that the transmission of high-risk genetic signals occurs in 60% of people of South Asian ancestry, which could provide an explanation for the huge increase in deaths among these groups across Britain, in addition to the impact that the Covid virus has had in India. .
The Oxford study revealed that the LZTFL1 gene is present in 15% of those of European descent, and only 2% of those of African-Caribbean descent. Scientists had identified a stretch of DNA that doubles the risk of death for adults under the age of 65 with the Corona virus.
However, the team of scientists did not know exactly how the genetic signal to increase the risk works, nor the nature of the genetic change responsible. However, genome-wide association studies are important for identifying candidate genes and pathways that predispose to complex diseases, and ultimately lead to approved drugs.
The researchers also noted that the LZTFL1 gene is also linked to type 1 diabetes, autoimmune disease and multiple sclerosis
The latest study was carried out by an artificial intelligence algorithm prepared by a team of scientists under the leadership and supervision of Professor James Davis and Professor Jim Hughes at the University of Oxford, who said that there is uncertainty about the effects that occur in the genome, and how health risks are formed, but it turns out that the danger lies In changes that affect DNA and make the dangerous gene active when infected with corona.
The study also showed that the genetic signal is likely to affect lung cells. The researchers used the technology to “amplify DNA” and identify the specific gene that was controlled by the sequence, which in turn caused an increased risk of severe and severe symptoms among some Corona patients