Good news for children and the faint of heart.. Corona vaccine without injections

Since the beginning of the pandemic, vaccination projects against COVID-19 with patches are increasing in a development that could revolutionize the way vaccines are administered in the future.
According to the French Press Agency, this technology may avoid crying crises when injecting children, but it has other benefits, most notably enhanced effectiveness and better spread.

A study conducted on mice, the results of which were recently published in the journal Science Advances, revealed promising results.
It was centered on a square plastic sticker that extends one centimeter in length and width and has more than 5,000 pointed heads on its surface, “too small to be seen,” said epidemiologist David Muller, who participated in the study conducted by the University of Queensland in Australia.

Scientist Muller holding a sticker

Scientist Muller holding a sticker

These heads are covered with the vaccine, which is transmitted to the skin when the patch is applied. The scientists used a vaccine that does not contain the whole virus, but rather one of its own proteins known as skeletal proteins. Mice were vaccinated with plasters (which were placed on their skin for two minutes) and others with needles.

In the first case, a strong response was obtained from the antibodies, including in the lung area, which is essential to combating corona, according to what researcher Muller revealed, stressing that “the results far exceeded those achieved by injection.”

In a second stage, the effectiveness of a single patch given was evaluated. And with the use of an immune-boosting drug, the mice never got sick

Vaccines are usually given by injection into the muscle, but the muscles do not store as many immune cells for an effective response as the skin does, Mueller said.
The pointed heads cause minor injuries that alert the body to a problem and then stimulate the immune response.

For the world, the benefits of this technology are clear, including that the vaccine can remain stable for a month at an average temperature of 25 degrees Celsius and for a week at a temperature of 40 degrees, compared to a few hours for the “Pfizer” and “Moderna” vaccines, which limits the use of a series of vaccines. Refrigeration is a challenge for developing countries.

It is also very easy to apply the stickers and there is no need for trained staff.
The label used in the study was made by the Australian company “Faxas”, the most advanced in this field. Phase one trials are expected from April

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